1-(Bromomethyl)-2-(difluoromethoxy)benzene, 2-(Bromomethyl)phenyl difluoromethyl ether
2-(difluoromethoxy)benzyl bromide
CAS: 85684-64-6
Molecular Formula: C8H7BrF2O
1-(Bromomethyl)-2-(difluoromethoxy)benzene, 2-(Bromomethyl)phenyl difluoromethyl ether - Names and Identifiers
1-(Bromomethyl)-2-(difluoromethoxy)benzene, 2-(Bromomethyl)phenyl difluoromethyl ether - Physico-chemical Properties
| Molecular Formula | C8H7BrF2O |
| Molar Mass | 237.04 |
| Density | 1,555 g/cm3 |
| Boling Point | 222°C |
| Flash Point | 108°C |
| Water Solubility | Immiscible with water. |
| Vapor Presure | 0.131mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Lachrymatory |
| Refractive Index | 1.518 |
| MDL | MFCD00190103 |
1-(Bromomethyl)-2-(difluoromethoxy)benzene, 2-(Bromomethyl)phenyl difluoromethyl ether - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2922 |
| Hazard Note | Corrosive/Lachrymatory |
| Hazard Class | 8 |
| Packing Group | III |
1-(Bromomethyl)-2-(difluoromethoxy)benzene, 2-(Bromomethyl)phenyl difluoromethyl ether - Introduction
2-(difluoromethoxy)benzyl bromide is an organic compound with the chemical formula C8H7BrF2O. It is a colorless to yellowish liquid with a special pungent odor at room temperature.
2-(difluoromethoxy)benzyl bromide is often used as an important intermediate in organic synthesis. It can be used in the field of medicine for the synthesis of drugs, such as anti-cancer drugs, antipsychotic drugs, anti-allergic drugs. In addition, it can also be used to synthesize pesticides, dyes and medical materials.
There are many methods for preparing 2-(difluoromethoxy)benzyl bromide. The common method is to react benzyl bromide with difluormethanol. The reaction is carried out under an acidic condition and is promoted by adding an ether solvent and a dilute sulfuric acid catalyst.
Regarding the safety information of 2-(difluoromethoxy)benzyl bromide, it is an irritant substance that may irritate the skin, eyes and respiratory system. Therefore, contact with skin and eyes should be avoided during operation, and good ventilation conditions should be ensured. At the same time, care must be taken to properly store and handle the compound to avoid contact with ignition sources or oxidizing agents.
2-(difluoromethoxy)benzyl bromide is often used as an important intermediate in organic synthesis. It can be used in the field of medicine for the synthesis of drugs, such as anti-cancer drugs, antipsychotic drugs, anti-allergic drugs. In addition, it can also be used to synthesize pesticides, dyes and medical materials.
There are many methods for preparing 2-(difluoromethoxy)benzyl bromide. The common method is to react benzyl bromide with difluormethanol. The reaction is carried out under an acidic condition and is promoted by adding an ether solvent and a dilute sulfuric acid catalyst.
Regarding the safety information of 2-(difluoromethoxy)benzyl bromide, it is an irritant substance that may irritate the skin, eyes and respiratory system. Therefore, contact with skin and eyes should be avoided during operation, and good ventilation conditions should be ensured. At the same time, care must be taken to properly store and handle the compound to avoid contact with ignition sources or oxidizing agents.
Last Update：2024-04-09 21:54:55
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CAS: 85684-64-6
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CAS: 85684-64-6
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